‘‘Inverse’’ synthesis of polymer bioconjugates using soluble supports

Paper published in Chem. Commun. together with Dr. Jean-Francois Lutz (Strasbourg).

Well-defined cleavable or non-cleavable soluble polystyrene supports were prepared by atom transfer radical polymerization and utilized for the iterative synthesis of functional hexapeptides. This approach allowed rapid and efficient liquid phase synthesis of peptide–polymer conjugates.