Calcium ions as bioinspired triggers to reversibly control the coil to helix transition in peptide-polymer conjugates

Paper to be published in Soft Matter A de novo designed calcium responsive peptide sequence was synthesized and the effect of conjugating poly (ethylene oxide) of different molecular weights on the calcium induced coil-to-helix transition was investigated. The secondary structure transition showed to be reversible upon addition of competitive calcium ion binders.

Soft Matter, DOI:10.1039/C1SM05625E