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Prof. Dr. habil. Hans Börner
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+49 (0)30 2093-7348 |
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+49 (0)30 2093-7500 |
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Contact Us |
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Laboratory for Organic Synthesis of Functional Systems
Department of Chemistry
Humboldt-Universität zu Berlin
Brook-Taylor-Str. 2
12489 Berlin
Germany
Sekretariat
Phone: +49 (0)30 2093-7349
Fax: +49 (0)30 2093-7215
Room: 0'144
Email
office.functional-systems hu-berlin.de |
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News
Toward Personalized Stationary Chromatography Phases: Equipping Commercial Silica Phases with Selected Peptide-Based Binding Domains to Tailor Affinity
06.01.2025 - Toward Personalized Stationary Chromatography Phases: Equipping Commercial Silica Phases with Selected Peptide-Based Binding Domains to Tailor Affinity
The last paper of Steffen Busche was released in Advanced Materials Interfaces.
The 7-mer peptide motifs QFFLFFQ, QFFEFFQ and QFQQSFF, known as good, medium and poor binders for the photosensitizers m-THPC and Chlorin E6 are covalently immobilized on commercial amino-functionalized silica particles by inverse electron-demand Diels-Alder ligation. After proof of compound binding by UV/Vis batch experiments, professionally packed HPLC columns show compound specific separation performance with clear differences in retention times.
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