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Electrosynthesis of mussel-inspired adhesive polymers as a novel class of transient enzyme stabilizers

New paper published in Angewandte Chemie by the electraDetouch team.
The electrochemical oxidation of multifunctional catechols represents a “green” and clean alternative pathway to ortho-quinones, which are used to form oligomer networks with branched multi-thiols. In these networks, the catechols are restored and represent adhesive points, which can establish transient interactions with enzymes. These oligomer/enzyme-conjugates are shielding the enzymes from heat stress, thus preventing denaturation. (https://doi.org/10.1002/anie.202419684)